The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes

We examined influences of conditioned media from chondrocytes (Ch) on juvenile idiopathic arthritis synovial fibroblasts (JFLS) and potential for JFLS to undergo endochondral bone formation (EBF).

Source: Pediatric Rheumatology - May 12, 2021 Category: Rheumatology Authors: Megan M. Simonds, Amanda R. Schlefman, Suzanne M. McCahan, Kathleen E. Sullivan, Carlos D. Rose and Anne Marie C. Brescia Tags: Research article Source Type: research