Gut-Lung Axis in COVID-19

Interdiscip Perspect Infect Dis. 2021 Mar 12;2021:6655380. doi: 10.1155/2021/6655380. eCollection 2021.ABSTRACTCOVID-19 is a pandemic infection of the respiratory system caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The viral ribonucleic acid (RNA) was found in many parts of the COVID-19 patients including the stool, suggesting a potential interaction with the host's gut microbiome. The gut microbiome also plays major roles in immunity and inflammation. It also impacts pulmonary functions through the gut-lung axis. There have been recent reports of the importance of the host microbiome in infection and pathogenicity. The understanding of the gut and lung microbiomes would open the gate to new therapeutic approaches.PMID:33777139 | PMC:PMC7979298 | DOI:10.1155/2021/6655380
Source: Interdisciplinary Perspectives on Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research