A Resting-state Functional Magnetic Resonance Imaging Study of Whole-brain Functional Connectivity of Voxel Levels in Patients With Irritable Bowel Syndrome With Depressive Symptoms

CONCLUSIONS: DEP-IBS patients have abnormal FC in brain regions associated with the fronto-limbic and sensorimotor networks, especially insula and SMA, which explains the vicious circle between negative emotion and gastrointestinal symptoms in IBS. Identification of such alterations may facilitate earlier and more accurate diagnosis of depression in IBS, and development of effective treatment strategies.PMID:33795543 | PMC:PMC8026363 | DOI:10.5056/jnm20209
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research