Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1

CONCLUSION: These results support a model in which ABI1-SiL plays an anti-oncogenic role by competitively binding to WAVE2 and directly interacting with phosphorylated and non-phosphorylated ABI1-p65, functioning as a dominant-negative form of ABI1-p65.PMID:33958846 | PMC:PMC8058658 | DOI:10.3748/wjg.v27.i15.1595
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research