Molecular mechanism of apelin-13 regulation of colonic motility in rats

In conclusion, apelin-13 inhibited the spontaneous contractile activity of isolated rat colons via the suppression of L-type calcium channels and BKCa channels in colonic smooth muscle cells.PMID:33961873 | DOI:10.1016/j.ejphar.2021.174149

Source: European Journal of Pharmacology - May 7, 2021 Category: Drugs & Pharmacology Authors: Lin Yan Haixia Ren Fangting Yuan Wenyao Shi Ying Wang Hesheng Luo Source Type: research