High BRCA2 Gene Expression is Associated with Aggressive and Highly Proliferative Breast Cancer

ConclusionsBRCA2 high gene expression was associated with highly proliferative and aggressive breast cancer that was highly immunogenic with better response to PARP inhibitors in ER-positive patients.BRCA2 gene expression may become a candidate marker for aggressive biology and to tailor specific treatment strategies in the future.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research