Imaging of Malignant Pleural Mesothelioma: Pearls and Pitfalls
Publication date: Available online 8 May 2021Source: Seminars in Ultrasound, CT and MRIAuthor(s): Chad D. Strange, Girish S. Shroff, Jitesh Ahuja, Ioannis Vlahos, Marcelo F.K. Benveniste, Mylene T. Truong
Conclusions: In ultrasound-guided needle biopsy for peripheral lung lesions, using a combination of linear and non-linear puncture techniques and keeping away from necrotic areas and large blood vessels, may help to increase the success rate and reduce the incidence of complications further. PMID: 32802449 [PubMed - as supplied by publisher]
We report the case of a 48 ‐year‐old man who presented with persistent right‐sided thoracic pain with chest computed tomography scan demonstrating a right‐sided pleural effusion and pleural mass invading the ribs. Ultrasound‐guided biopsy revealed a primary squamous cell carcinoma of the pleura. Positron emission to mography staging demonstrated metastatic lung and lymph node involvement precluding surgical therapy. Immunotherapy with nivolumab resulted in prolongation of survival with good quality of life. Malignant pleural effusions usually manifest in the course of metastatic cancer disease. Primary pleural tu...
In conclusion, we hereby demonstrate that EUS‐B‐FNA from pleural lesions is feasible and appears to be safe.
Conclusion: Our experience is that non-lung primary carcinoma is not uncommonly diagnosed via EBUS, removing the need for invasive investigations and ensuring correctly targeted systemic oncological treatment. Further studies with pooling of data from multiple centres are required to study this area.
tro A PMID: 31740084 [PubMed - as supplied by publisher]
CONCLUSIONS: The exact diagnosis of these lesions is difficult due to their rarity and they must always be considered for differential diagnosis. PMID: 31697257 [PubMed - in process]
A 37-year-old woman, gravida 0, virgin, who was a hepatitis B carrier with a medical history of childhood asthma consulted our department because of a gradual increase in the size of left ovarian mass that was diagnosed 3 years ago; she had recently developed menorrhagia. Transvaginal ultrasound revealed a unilocular cyst measuring 7.5 × 6.7 cm, with diffuse homogeneous ground-glass echoes in the left ovary (Fig. 1), suggesting endometrioma. The level of tumor marker antigen carbohydrate 125 (CA-125) was 56.8 U/ml.
CONCLUSIONS: CLE imaging was feasible and safe regardless of the biopsy method. Real-time visualization of pleural abnormalities in epithelial and sarcomatoid MPM, could be distinguished from pleural fibrosis. Therefore, CLE has potential as a guidance biopsy tool, to reduce the current substantial rate of repeat biopsy procedures, by identification of areas with malignant cells in vivo (smart needle). PMID: 31075217 [PubMed - as supplied by publisher]
Conclusions: EBUS-TBNA mediastinal LN staging may impact significantly management of patients with MPM by detecting mediastinal metastatic disease, therefore, preventing morbidity and mortality of surgical management. PMID: 30963005 [PubMed]
Conditions: Mesothelioma; Peritoneal Mesothelioma Interventions: Diagnostic Test: HR-MRI; Diagnostic Test: Standard CT Imaging; Diagnostic Test: Ultrasound Sponsor: University of Chicago Not yet recruiting