Utility of Surveillance Ambulatory Rhythm Monitoring in the Pediatric Fontan Population

AbstractOur institution established a Fontan surveillance plan, which included ambulatory rhythm monitoring (ARM) at 6, 10, 13, 16 and 19 years old, for early detection of Fontan-associated complications. We conducted a retrospective chart review of Fontan patients followed at our institution 2014 –2018 to determine the utility of surveillance ARMs. 139 ARMs from 83 patients were included. ARMs with supraventricular tachycardia, sinus node dysfunction, accelerated junctional rhythm, >  1st degree atrioventricular block, and complex ventricular ectopy were classified as positive for arrhythmia. Arrhythmias were occult if detected on surveillance ARM. The ARM indication was surveillance in 78 (56%) and clinically indicated in 61 (44%). 52 (37%) ARMs in 27 (33%) patients had an ar rhythmia. There was no difference in the age of patients with and without arrhythmias [median 10.9 (6.5, 17.1 years) vs. 8.8 (7, 13.6 years),p = 0.5]. Clinically indicated ARMs more frequently demonstrated arrhythmias than surveillance ARMs (52% vs. 26%,p <  0.01). Compared to patients without arrhythmias, those with arrhythmias were more likely to be female (48% vs. 23%,p = 0.02), have a single right ventricle (46% vs. 19%,p <  0.01) and longer QRS duration on ECG [100 (91, 116 ms) vs. 94 (84, 104 ms),p = 0.046]. Patients with occult arrhythmias were less likely to have moderate to severe atrioventricular valvar regurgitation (0% vs. 46%;p = 0.04) or ventricular ...
Source: Mammalian Genome - Category: Genetics & Stem Cells Source Type: research