Is there a role for doravirine in African HIV treatment programmes? A large observational resistance study in South Africa

CONCLUSIONS: Although doravirine is approved as initial therapy in patients who are ART-naïve, it is currently recommended to obtain a genotype prior to the initiation of ART. Clinical studies are needed to ascertain whether predicted resistance profiles in ART naïve and NNRTI-treated patients translate into poor clinical outcomes, especially in settings where genotypic resistance testing is not available.PMID:33943000 | DOI:10.1002/jia2.25706
Source: Journal of the International AIDS Society - Category: Infectious Diseases Authors: Source Type: research