This month in The Journal

Tandem repeats make up ~3% of the human genome, but owing to their repetitive, mutagenic, and polymorphic nature, these elements have been largely overlooked in high-throughput genomic studies. Although the contribution of tandem repeats to human disease has been recognized for decades, only recently have researchers been able to explore in a genome-wide fashion the phenotypic consequences of variation within tandem repeats. In this issue, Garg et  al. assess the putative functional effects of copy-number variation in variable number tandem repeats (VNTRs).

Source: The American Journal of Human Genetics - May 6, 2021 Category: Genetics & Stem Cells Authors: Sarah Ratzel, Sara B. Cullinan Tags: Editors' Corner Source Type: research