Organized structure of real-world evidence best practices: moving from fragmented recommendations to comprehensive guidance

J Comp Eff Res. 2021 Apr 30. doi: 10.2217/cer-2020-0228. Online ahead of print.ABSTRACTDecision-makers have become increasingly interested in incorporating real-world evidence (RWE) into their decision-making process. Due to concerns regarding the reliability and quality of RWE, stakeholders have issued numerous recommendation documents to assist in setting RWE standards. The fragmented nature of these documents poses a challenge to researchers and decision-makers looking for guidance on what is 'high-quality' RWE and how it can be used in decision-making. We offer researchers and decision-makers a structure to organize the landscape of RWE recommendations and identify consensus and gaps in the current recommendations. To provide researchers with a much needed pathway for generating RWE, we discuss how decision-makers can move from fragmented recommendations to comprehensive guidance.PMID:33928789 | DOI:10.2217/cer-2020-0228

Source: Journal of Comparative Effectiveness Research - April 30, 2021 Category: General Medicine Authors: Ashley Jaksa James Wu P áll Jónsson Hans-Georg Eichler Sarah Vititoe Nicolle M Gatto Source Type: research