Study: Breast-conserving surgery offers better survival than mastectomy for cancer

Women who undergo breast-conserving surgery and radiation therapy for breast cancer are more likely to survive the disease than those who receive a full mastectomy, a study published Wednesday by JAMA Surgery found.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Ann Surg Oncol. 2021 Sep 6. doi: 10.1245/s10434-021-10730-7. Online ahead of print.ABSTRACTBACKGROUND: Little is known about the surgical patterns of American Indian/Alaska Native (AI/AN) breast cancer patients. The purpose of this study is to determine whether there are disparities in breast cancer surgery and radiation therapy between non-Hispanic AI/AN (NH-AI/AN) women and non-Hispanic White (NHW) women.METHODS: Data from the National Program of Cancer Registries of the Centers for Disease Control and Surveillance, Epidemiology, and End Results were used for this cross-sectional study. Female patients with invasive brea...
Source: Ann Oncol - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: Identification and false-negative rates for SLNB were comparable to those in female breast cancer. Breast-conserving surgery can be effective and safe; postmastectomy radiation to the chest wall and 5-year tamoxifen treatment improves survival.PMID:34476472 | DOI:10.1093/bjs/znab279
Source: The British Journal of Surgery - Category: Surgery Authors: Source Type: research
CONCLUSION: RT-induced changes in hydration, sebum, and melanin, and the majority of patient-reported pain, color changes, and dryness, even 3 months after the completion of treatment. There were no remarkable differences in the measurable skin parameters according to the surgery type, with the exception of erythema, which was higher in the MRM group 1 week after the start of RT.PMID:34400081 | DOI:10.1016/j.clbc.2021.06.013
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
esco Franco In the current study, we sought to compare survival outcomes after breast-conserving therapy (BCT) or mastectomy alone in patients with stage I-IIA breast cancer, whose tumors are typically suitable for both locoregional treatments. The study cohort consisted of 1360 patients with stage I-IIA (T1–2N0 or T0–1N1) breast cancer diagnosed between 2001 and 2013 and treated with either BCT (n = 1021, 75.1%) or mastectomy alone (n = 339, 24.9%). Median follow-ups for disease-free survival (DFS) and overall survival (OS) were 6.9 years (range, 0.3–15.9) and 7.5 years (range, 0.2–25.9), respe...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
CONCLUSION: Radiotherapy use in EBC patients ≥70 years is affected by age and recurrence risk, whereas geriatric parameters have limited impact regardless of type of surgery. There was geographical variation in treatment, with some fit older women with high-risk tumours not receiving radiotherapy, and some older, low-risk, EBC patients receiving radiotherapy after BCS despite evidence of limited benefit. The impact on HRQoL is transient.PMID:34146616 | DOI:10.1016/j.radonc.2021.06.021
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Source Type: research
Breast cancer is the most common cause of cancer-related deaths for women worldwide with an overall increasing trend of prevalence and mortality rate [1,2]. Breast conserving surgery (BCS) plus radiation therapy (RT) or mastectomy have shown comparable oncological outcomes in early-stage breast cancer and are considered standard of care treatment to be offered to patients based on the specific disease presentation [3,4]. Although both interventions are valid options, mastectomy should not be regarded as equal to breast conservation [5].
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Tumour Review Source Type: research
Breast cancer is the most common cause of cancer-related deaths for women worldwide with an overall increasing trend of prevalence and mortality rate [1,2]. Breast conserving surgery (BCS) plus radiation therapy (RT) or mastectomy have shown comparable oncological outcomes in early-stage breast cancer and are considered standard of care treatment to be offered to patients based on the specific disease presentation [3,4]. Although both interventions are valid options, mastectomy should not be regarded as equal to breast conservation [5].
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Tumour Review Source Type: research
The oncology community has advocated in favor of breast-conserving surgery (BCS) as an alternative to mastectomy in appropriately selected patients with breast cancer for several decades. This recommendation is supported by multiple prospective randomized clinical trials demonstrating overall survival equivalence for both operative approaches and is aligned with the paradigm shift in oncology to de-escalate all components of multidisciplinary care. Medical breast oncologists use less chemotherapy as a consequence of improved risk stratification by gene expression profiling and surgical breast oncology has also evolved. Tod...
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
CONCLUSION: We suggest that repeated BCS with radiation therapy deserves consideration when DCIS survivors suffered IBTR. The choice of surgical management should be tailored based on patients' age at IBTR diagnosis and size of recurrent disease.PMID:33846099 | DOI:10.1016/j.clbc.2021.02.012
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
We report a case of breast angiosarcoma with a preoperative diagnosis of late recurrence of breast cancer. A 78-year-old woman noticed a tumor in her right breast and visited our hospital. The patient had undergone breast-conserving surgery and axillary lymph node dissection from the right breast 12 years before the visit. The tumor was diagnosed as T4bN0M0, stage IIIB. Anastrozole was administered as postoperative adjuvant therapy for 5 years; the patient also received 50-Gy whole-breast radiation therapy after surgery. Physical examination during her visit revealed an elevated lesion with blue purpura around the nipple i...
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
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