Sign- and goal-tracking score does not correlate with addiction-like behavior following prolonged cocaine self-administration

ConclusionsPhenotyping along a continuum of PCA scores may not be a valid predictor for identifying vulnerability to the addiction-like behaviors examined using the 3-CRIT model. However, PCA phenotype may predict a single feature of the 3-CRIT model, resistance to punishment, among those rats classified as either STs or GTs.
Source: Psychopharmacology - Category: Psychiatry Source Type: research