Exposure to DMSO during infancy alters neurochemistry, social interactions, and brain morphology in long ‐evans rats
ConclusionsDespite short ‐term exposure at low, putatively nontoxic concentrations, DMSO led to changes in behavior and social preferences, chronic alterations in glial cells, and changes in essential regulatory brain metabolites. The chronic neurological effects of DMSO exposure reported here raise concerns about its neu rotoxicity and consequent safety in human medical applications and clinical trials.
Source: Brain and Behavior - Category: Neurology Authors: Zachary Rabow,
Taryn Morningstar,
Megan Showalter,
Hailey Heil,
Krista Thongphanh,
Sili Fan,
Joanne Chan,
Ver ónica Martínez‐Cerdeño,
Robert Berman,
David Zagzag,
Evgeny Nudler,
Oliver Fiehn,
Mirna Lechpammer Tags: ORIGINAL RESEARCH Source Type: research