Efficacy of statins on renal function in patients with chronic kidney disease: a systematic review and meta-analysis

CONCLUSIONS: We found that statin use in patients with CKD may slow CKD progression by lowering urinary albumin and protein excretions or increasing creatinine clearance. Further large-scale RCTs should be conducted to evaluate the long-term effects of statins on renal outcomes. Abbreviations: CKD: chronic kidney disease; RCT: randomized controlled trials; WMD: weighted mean differences; CI: confidence intervals; ACEI: angiotensin-converting enzyme inhibitors; eGFR: estimated glomerular filtration rate.PMID:33926359 | DOI:10.1080/0886022X.2021.1915799
Source: Renal Failure - Category: Urology & Nephrology Authors: Source Type: research