Interferon- τ regulates the expression and function of bovine leukocyte antigen by downregulating bta-miR-204

In conclusion, IFN-τ may function by suppressing the expression of bta-miR-204 to increase the expression of BoLA during the embryo implantation period in cattle. IFN-τ may induce PD-L1 and PD-L2 transcription by regulating BoLA, which may influence the T cell immune response, thereby regulating pregnant cattle immunization.PMID:33884032 | PMC:PMC8056107 | DOI:10.3892/etm.2021.10026
Source: Experimental and Therapeutic Medicine - Category: General Medicine Authors: Source Type: research