LOXL1 ‑AS1 promotes thymoma and thymic carcinoma progression by regulating miR‑525‑5p‑ < em > HSPA9 < /em >

In conclusion, LOXL1‑AS1 and HSPA9 are highly expressed in thymoma and thymic carcinoma; miR‑525‑5p is expressed at low levels in thymoma and thymic carcinoma; and downregulation of miR‑525‑5p is associated with poor prognosis. In summary, this study demonstrates that LOXL1‑AS1 acts as a sponge that targets miR‑525‑5p to promote HSPA9 expression, thereby promoting the growth and invasion and inhibiting apoptosis of thymoma and thymic carcinoma cells.PMID:33907842 | DOI:10.3892/or.2021.8068
Source: Oncology Reports - Category: Cancer & Oncology Authors: Source Type: research