Case report: colchicine toxicokinetic analysis in a poisoned child requiring extracorporeal life support - P érez Marín M, Prod'hom S, de Villiers SF, Ferry T, Amiet V, Natterer J, Perez MH, Buclin T, Chtioui H, Longchamp D.

Colchicine poisoning is associated with a poor prognosis, especially when leading to shock and multi-organ failure, and management is limited to supportive care, including multiple-dose activated charcoal. At therapeutic concentrations, colchicine eliminat...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

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Organophosphorous Insecticides (OPIs) have been profusely used and toxicity by them are common. Scoring systems are used as predictors of survival in severely ill patients. OPIs toxicity is associated with multiple biochemical abnormalities like changes in...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Pesticides are known human and environmental toxicants, with an estimated 3 million cases of pesticide poisoning happening every year globally, resulting in more than 250,000 deaths. According to the existing literature, different pesticides groups are rea...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
In recent years, alcohol use disorders have been on the rise globally which is seen as a global issue. Alcohol consumption has many side effects and consequently various damages. In the past several years, various programs for the treatment of alcohol use ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Studies suggest that acute pesticide poisonings (APP) may be linked with long-term neurological effects. To examine long-term neurological and psychological distress symptoms associated with having experienced an APP, we conducted a cross-sectional study o...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
The mu opioid receptor antagonist naloxone has been a vital, long-standing countermeasure in the ongoing battle against opioid use disorders (OUD) and toxicity. However, due to its distinctive short elimination half-life, naloxone has shown diminished effi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
CONTEXT: Pregabalin poisoning is mostly benign, although coma and convulsions occasionally occur. AIM: To determine the dose-toxicity relationship of pregabalin. METHODS: Dose-toxicity data of isolated pregabalin poisonings was collected fr...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Xylazine is a drug used in veterinary medicine as an animal sedative with muscle relaxant and analgesic properties (1). It is not approved by the Food and Drug Administration for use in humans, in whom it acts as a central nervous system depressant and can...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Poisoning Source Type: news
Five Oregonians were hospitalized recently after consuming ivermectin, a potent antiparasitic drug that they took in hopes of preventing or treating Covid-19, Oregon Health&Science University announced Friday. The Oregon Poison Center has managed 25 cases involving Oregonians who intentionally misused ivermectin between Aug. 1 and Sept. 14. There is no clinical data supporting its use for Covid-19, nor is it approved for such use. Five cases involved hospitalization, with two people so severely…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Poison control centers dealt with more cases of people abusing the antiparasitic ivermectin, which has been falsely touted as a Covid-19 cure, in August than they did for the whole of 2019 or 2020.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Tags: Business /business Innovation /innovation Healthcare /healthcare Breaking breaking-news Editors' Pick editors-pick Dashboard Coronavirus Source Type: news
Staphylococcus aureus (S. aureus) is the top ordinary pathogen causing epidemic and food poisoning. The authentication of S. aureus has great significance for pathologic diagnosis and food hygiene supervision. Various biosensor methods have been established for identification. This paper reviews the research progress of aptasensors for S. aureus detection, focusing on the classification of aptamer technologies, including optical aptasensors and electrochemical aptasensors. Furthermore, the feasibility and future challenges of S. aureus detection for aptamer assays are discussed. Combining aptasensors with nanomaterials app...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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