NRF2 activation putatively mediates clinical benefits of low-dose radiotherapy in COVID-19 pneumonia and acute respiratory distress syndrome (ards): novel mechanistic considerations

The SARS CoV-2 virus that causes COVID-19 has proven to be problematic to effectively contain, treat, and manage given extant protocols and policies of the international medical and public health communities. The virus ’s sudden occurrence, high infectivity, variant morbidity, lethality, potential mutability, and heretofore lack of safe and effective treatments or vaccines, have all contributed to, and exacerbated public-health challenges throughout the world. Although apparently effective vaccines are now avail able, there is ongoing consideration and concern about their provision and durability, as well as public willingness to accept them.

Source: Radiotherapy and Oncology - April 28, 2021 Category: Radiology Authors: Edward J. Calabrese, Walter J. Kozumbo, Rachna Kapoor, Gaurav Dhawan, Pedro C. Lara Jimenez, James Giordano Tags: Review Article Source Type: research