Tissue distribution of epirubicin after severe extravasation in humans

ConclusionSurgical intervention after demarcation of the extravasation lesion allows for almost uninterrupted continuation of treatment independent of the amount of extravasated anthracycline. As even minor amounts of the vesicants may trigger tissue necrosis, preventive measures merit the highest priority.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research