Role of pirfenidone in TGF- β pathways and other inflammatory pathways in acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection: a theoretical perspective

CONCLUSION: The drug as a theoretical perspective may be an effective and safe choice for suppressing the inflammatory response during COVID-19. The recommendation would be a combination of pirfenidone and N-acetylcysteine to achieve maximum benefit during SARS-CoV-2 treatment.PMID:33880743 | PMC:PMC8057922 | DOI:10.1007/s43440-021-00255-x
Source: Pharmacological Reports - Category: Drugs & Pharmacology Authors: Source Type: research