Characterizing the relationship between the chemical structures of drugs and their activities on primary cultures of pediatric solid tumors

CONCLUSION: It is possible to identify privileged chemical scaffolds and predict the in vitro potency of unseen molecules across these 30 targets This information and models should be helpful to select which molecules to screen against these primary cultures of pediatric solid tumors.PMID:33874867 | DOI:10.2174/0929867328666210419134708

Source: Current Medicinal Chemistry - April 20, 2021 Category: Chemistry Authors: Saw Simeon Ghita Ghislat Pedro Ballester Source Type: research