Targeting MCL-1 in cancer: current status and perspectives

Myeloid leukemia 1 (MCL-1) is an antiapoptotic protein of the BCL-2 family that prevents apoptosis by binding to the pro-apoptotic BCL-2 proteins. Overexpression of MCL-1 is frequently observed in many tumor t...

Source: Journal of Hematology and Oncology - April 21, 2021 Category: Hematology Authors: Haolan Wang, Ming Guo, Hudie Wei and Yongheng Chen Tags: Review Source Type: research