aImpact of radiation-induced toxicities on quality of life of patients treated for head and neck cancer

In recent years, considerable progress has been made in the development of prediction models for radiation-induced toxicities for head and neck cancer (HNC) [1]. Multivariable prediction models can be used to predict a wide range of normal tissue complication probabilities (NTCP) [2]. These models can provide guidance in treatment plan optimization [3,4], treatment plan comparison and in the selection of patients for new radiation technologies, such as for proton therapy [5,6]. Knowledge on the optimal dose distribution, i.e., the order in which organs at risk (OAR) should be spared to avoid toxicities, is crucial [7].

Source: Radiotherapy and Oncology - April 20, 2021 Category: Radiology Authors: Hans Paul van der Laan, Lisa Van den Bosch, Ewoud Schuit, Roel J.H.M. Steenbakkers, Arjen van der Schaaf, Johannes A. Langendijk Tags: Original Article Source Type: research