A degraded state of consciousness in healthy awake humans?

The perturbational complexity index (PCI) measures the spatiotemporal dynamics of transcranial magnetic stimulation (TMS)-evoked electroencephalography (EEG) potentials (TEPs)1. High PCI values reflect the joint presence of integration and differentiation in thalamocortical networks of conscious brains1. Low PCI values have been reported during natural non-rapid eye movement sleep, in disorders of consciousness, and during unresponsiveness caused by general anesthetics2,3. The PCI can reliably dissociate different states of unconsciousness in a graded fashion1,3.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research