Optimization binding studies of opioid receptors, saturation and competition, using [ < sup > 3 < /sup > H]-DAMGO

CONCLUSION: Applying the centrifugation method instead of the filtration to separate free from bound radioligand produced repeatable and reliable results. The optimum conditions for radioligand binding were used in competition studies which resulted in the expected outcomes.PMID:33871815 | DOI:10.1007/s43440-021-00265-9

Source: Pharmacological Reports - April 19, 2021 Category: Drugs & Pharmacology Authors: Mona Khoramjouy Fatemeh Ahmadi Mehrdad Faizi Soraya Shahhosseini Source Type: research