Select antitumor cytotoxic CD8 < sup > + < /sup > T clonotypes expand in patients with chronic lymphocytic leukemia treated with ibrutinib

CONCLUSIONS: In patients with CLL, established T-cell responses directed against tumor are suppressed by disease and reactivated by ibrutinib.PMID:33875521 | DOI:10.1158/1078-0432.CCR-20-4894

Source: Clinical Lung Cancer - April 20, 2021 Category: Cancer & Oncology Authors: Maria Joao Baptista Sivasubramanian Baskar Erika M Gaglione Keyvan Keyvanfar Inhye Ahn Adrian Wiestner Clare Sun Source Type: research