Phylogenetic classification of the whole-genome sequences of SARS-CoV-2 from India & amp; evolutionary trends

CONCLUSIONS: This study interpreted the geographical and temporal dominance of SARS-CoV-2 strains in India over a period of nine months based on the GISAID classification. An integration of the GISAID, Nextstrain and Pangolin classifications is also provided. The emergence of new lineages B.1.1.8 and B.1.113 was indicative of host-specific evolution of the SARS-CoV-2 strains in India. The hotspot mutations such as those driven by positive selection need to be further characterized.PMID:33818474 | DOI:10.4103/ijmr.IJMR_3418_20

Source: Indian J Med Res - April 5, 2021 Category: Research Authors: Varsha Potdar Veena Vipat Ashwini Ramdasi Santosh Jadhav Jayashri Pawar-Patil Atul Walimbe Sucheta S Patil Manohar L Choudhury Jayanthi Shastri Sachee Agrawal Shailesh Pawar Kavita Lole Priya Abraham Sarah Cherian ICMR-NIV NIC Team Source Type: research