Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial

CONCLUSION In ASA 1 and 2 patients receiving Nociception Level Index-guided antinociception, dexmedetomidine decreases intra-operative remifentanil requirements. Combined frontal electroencephalogram and Nociception Level Index monitoring can measure dexmedetomidine's hypnotic and opioid-sparing effects during remifentanil-propofol target-controlled infusion anaesthesia. TRIAL REGISTRATIONS Clinicaltrials.gov: NCT03912740, EudraCT: 2018-004512-22.
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Pain Source Type: research