Prognostic Implications of ALDH1 and Notch1 in Different Subtypes of Oral Cancer

CONCLUSION: The strong immunoexpression of Notch1 can contribute to identification of patients with poorly differentiated oral squamous cell carcinoma, who have perineural infiltration or lymph node metastasis. In addition, the strong immunoexpression of ALDH1 may help to identify a worse prognosis in patients with oral squamous cell carcinoma and their subtypes.PMID:33854547 | PMC:PMC8020805 | DOI:10.1155/2021/6663720

Source: Journal of Oncology - April 15, 2021 Category: Cancer & Oncology Authors: Silas Antonio Juvencio de Freitas Filho Cl áudia Malheiros Coutinho-Camillo Katia Klug Oliveira B árbara Beltrame Bettim Cl óvis Antônio Lopes Pinto Luiz Paulo Kowalski Denise Tostes Oliveira Source Type: research