Clioquinol Attenuates Pulmonary Fibrosis Through Inactivation of Fibroblasts via Iron Chelation

In conclusion, our study demonstrated that CQ, acting as an iron chelator, attenuates experimental PF through inactivation of fibroblasts, providing support for targeting iron metabolism as a basis for PF treatment.PMID:33861690 | DOI:10.1165/rcmb.2020-0279OC

Source: Mol Biol Cell - April 16, 2021 Category: Molecular Biology Authors: Yumeng Zhu Jing Chang Ke Tan Steven K Huang Xin Liu Xiaofan Wang Mengshu Cao Hongmin Zhang Shuxin Li Xianglin Duan Yanzhong Chang Yumei Fan Pengxiu Cao Source Type: research