Fixed dexmedetomidine infusion versus fixed-dose midazolam bolus as primary sedative for maintaining intra-procedural sedation during endobronchial ultrasound-guided transbronchial needle aspiration: a double blind randomized controlled trial

Conclusion: Fixed dexmedetomidine infusion statistically significantly reduced need for rescue sedation during EBUS-TBNA, and allowed slightly faster post-procedure recovery, as compared to fixed-dose midazolam bolus. However, it caused hypotension and bradycardia more frequently.Clinical trial registration: www.clinicaltrials.gov identifier is NCT02713191.PMID:33849367 | DOI:10.1080/17476348.2021.1918000

Source: Expert Review of Respiratory Medicine - April 14, 2021 Category: Respiratory Medicine Authors: Renu Kumari Kajal Jain Ritesh Agarwal Sahajal Dhooria Inderpaul Singh Sehgal Ashutosh Nath Aggarwal Source Type: research