Desmopressin as a novel long-term treatment in postural tachycardia syndrome patients with polyuria

Hypovolaemia is a well-recognized phenotype in patients with postural tachycardia syndrome (POTS). Previous work has identified paradoxical low renin-aldosterone levels as well as red blood cell deficit to indicate a potential renal cause for postural tachycardia syndrome.1 Here we present the first published report of postural tachycardia syndrome exacerbation due to partial central diabetes insipidus (pCDI) related polyuria and hypovolaemia; and successful treatment following chronic desmopressin (DDAVP) therapy.

Source: The American Journal of Medicine - April 15, 2021 Category: General Medicine Authors: Marie-Claire Seeley, Tilenka R. Thynne, Wilton J Braund, Daniel L Worthley, Celine Gallagher, Prashanthan Sanders, Dennis H. Lau Tags: Clinical Communication to the Editor Source Type: research