Trastuzumab emtansine (T-DM1) versus trastuzumab in Chinese patients with residual invasive disease after neoadjuvant chemotherapy and HER2-targeted therapy for HER2-positive breast cancer in the phase 3 KATHERINE study

ConclusionsIn the KATHERINE study, T-DM1 demonstrated increased efficacy compared to trastuzumab in Chinese patients. Consistent with previous data in Asian patients, T-DM1 was associated with more grade  ≥ 3 AEs, and AEs leading to discontinuation, which was driven by an increase in thrombocytopenia.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research