Clinical significance of T lymphocyte subsets, immunoglobulin and complement expression in peripheral blood of children with steroid-dependent nephrotic syndrome/frequently relapsing nephrotic syndrome
CONCLUSION: Renal function decline and inflammatory response existed in children with NS. CD3+, CD4+, CD4+/CD8+ and IgG/IgM in peripheral blood were decreased, while IgA, IgM, C3 and urinary CD80 were increased. Moreover, renal function decline, increase of inflammatory factors, decrease of IgG/IgM and CD4+/CD8+ were more obvious in the SDNS/FRNS group.PMID:33841716 | PMC:PMC8014369
Source: American Journal of Translational Research - Category: Research Authors: Shulian Chen Jianxin Wang Shishan Liang Source Type: research