Diversity of 3 ′ variable region of cagA gene in Helicobacter pylori strains isolated from Chinese population

ConclusionsIn this study, 503 CagA sequences were studied and analyzed in depth. In Chinese population, mostH. pylori strains were of the CagA-ABD subtype and its presence was associated with gastroduodenal diseases. Amino acid polymorphisms at residues 893 and 894 flanking the EPIYA motifs had a statistically significant association with gastric cancer.
Source: Gut Pathogens - Category: Microbiology Source Type: research