E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation [Immunology and Inflammation]

During an acute viral infection, CD8 T cells encounter a myriad of antigenic and inflammatory signals of variable strength, which sets off individual T cells on their own differentiation trajectories. However, the developmental path for each of these cells will ultimately lead to one of only two potential outcomes after...

Source: Proceedings of the National Academy of Sciences - April 15, 2021 Category: Science Authors: David M. Schauder, Jian Shen, Yao Chen, Moujtaba Y. Kasmani, Matthew R. Kudek, Robert Burns, Weiguo Cui Tags: Immunology and Inflammation Biological Sciences Source Type: research