Endoscopic full-thickness resection versus endoscopic submucosal dissection in the treatment of colonic neoplastic lesions  ≤ 30 mm—a single-center experience

AbstractEndoscopic full-thickness resection (FTR) is a novel technique of endoscopic treatment of colorectal neoplastic lesions not suitable for endoscopic polypectomy or mucosal resection. FTR appears to be a reasonable alternative to technically demanding endoscopic submucosal dissection (ESD) for lesions  ≤ 30 mm. However, comparison between FTR and ESD has not been published yet and their mutual positioning in the treatment algorithm is still unclear. The purpose of the analysis was to evaluate efficacy and safety of FTR in the treatment of colorectal lesions ≤ 30 mm by comparing pros pectively followed FTR cohort to retrospective ESD cohort in the setting of single tertiary endoscopy center. Primary outcomes were technical success rate, R0 resection and curative resection rate, and complication rate. A total of 52 patients in FTR and 50 patients in ESD group were treated between 2015 and 2018. Technical success rate was significantly higher in FTR group (92 vs. 74%,P = 0.01) as well as R0 resection rate (85 vs. 62%,P = 0.01) and curative resection rate (75 vs. 56%,P = 0.01). Complications occurred more frequently in ESD group (40 vs. 13%,P = 0.002), mainly due to high incidence of electrocoagulation syndrome (24 vs. 0%). Total procedure time was substantially shorter in FTR group (26.4 ± 11.0 min vs. estimated 90–240 min). Local residual neoplastic lesions were detected numerically more often in FTR group (12 vs. 5%,P = 0.12). N...

Source: Surgical Endoscopy - April 15, 2021 Category: Surgery Source Type: research