Phage-Targeting PCR Test Picks Up Early Lyme Disease Phage-Targeting PCR Test Picks Up Early Lyme Disease

Promising data show that a viral gene in the Lyme disease-causing bacteria can distinguish between early and late infection.Medscape Medical News
Source: Medscape Rheumatology Headlines - Category: Rheumatology Tags: Infectious Diseases News Source Type: news

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This study suggests that an adapted training-of-trainers is a feasible approach to raising tick and LD risk awareness among Qu ébec outdoor workers and public. Trained ambassadors have the potential of reaching a large portion of the population visiting or working in outdoor parks while also providing much-needed outreach regarding risk and prevention. Pushing this concept further to include other types of workers and juri sdictions may contribute to national LD surveillance efforts.
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research
Lyme borreliosis is a multisystemic disease caused by the pleomorphic bacteria of the Borrelia burgdorferi sensu lato complex. The exact mechanisms for the infection to progress into a prolonged sequelae of the disease are currently unknown, although immune evasion and persistence of the bacteria in the host are thought to be major contributors. The current study investigated B. burgdorferi infection processes in two human cell lines, both non-immune and non-phagocytic, to further understand the mechanisms of infection of this bacterium. By utilizing light, confocal, helium ion, and transmission electron microscopy, borrel...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Radiologia (Engl Ed). 2021 Sep-Oct;63(5):425-435. doi: 10.1016/j.rxeng.2021.07.002.ABSTRACTInfections of the central nervous system caused by atypical bacteria are becoming more common. Borrelia burgdorferi and Rickettsia conorii are microorganisms transmitted by ticks; infection with these bacteria result in a wide spectrum of manifestations on imaging. In areas where these tick-borne microorganisms are endemic, including Spain, these infections must be included in the differential diagnosis of patients with a variety of systemic and neurologic symptoms. The clinical presentation of these infections is nonspecific, and CT...
Source: Radiologia - Category: Radiology Authors: Source Type: research
AbstractThe chemokine CXCL13 is used as complement to serology in the diagnostics of Lyme neuroborreliosis (LNB). We evaluated and compared the semi-quantitative, cassette-based ReaScan CXCL13 assay with the quantitative recomBead CXCL13 assay using a collection of 209 cerebrospinal fluid samples. The categorical agreement between results interpreted as negative, grey zone, and positive by the two methods was 87%. The diagnostic sensitivity was higher using the recomBead assay, whereas specificity was higher using ReaScan. Few manual steps, and a short turn-around time with no batching of samples makes the ReaScan CXCL13 a...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Erythema migrans (EM) is the most common manifestation of Lyme borreliosis. Here, we examined EM patients in Norwegian general practice to find the proportion exposed to tick-transmitted microorganisms other t...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research Source Type: research
An exciting new finding by. Dr. Kim Lewis of Northeastern University gives hope that Lyme disease can be potentially treated without harming the microbiome.(PRWeb October 07, 2021)Read the full story at https://www.prweb.com/releases/global_lyme_alliance_congratulates_dr_kim_lewis_on_groundbreaking_publication_a_selective_antibiotic_for_lyme_disease/prweb18247374.htm
Source: PRWeb: Medical Pharmaceuticals - Category: Pharmaceuticals Source Type: news
Lyme disease, a tick-borne illness that is becoming more common in many countries, could be eradicated using a drug that kills the disease-causing bacterium
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Mil Med. 2021 Oct 6:usab420. doi: 10.1093/milmed/usab420. Online ahead of print.ABSTRACTLyme disease is a vector-borne infection that can affect multiple different organ systems. Lyme carditis represents one of these sequelae and is defined by acute onset of high-grade atrioventricular block in the presence of laboratory-confirmed infection. Current guidelines recommend patients with Lyme carditis be admitted for close cardiac monitoring and intravenous antibiotics therapy. Our case illustrates an active duty male who was initially diagnosed with Lyme disease after initially reporting symptoms including headache, fever, ey...
Source: Military Medicine - Category: International Medicine & Public Health Authors: Source Type: research
Nature, Published online: 06 October 2021; doi:10.1038/d41586-021-02716-yHygromycin A doesn’t work well against most bacteria, but it shines as a treatment for Lyme disease.
Source: Nature AOP - Category: Research Source Type: research
Vector-Borne and Zoonotic Diseases, Ahead of Print.
Source: Vector-Borne and Zoonotic Diseases - Category: Infectious Diseases Authors: Source Type: research
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