The known burden of Huntington disease in the North of Scotland: prevalence of manifest and identified pre-symptomatic gene expansion carriers in the molecular era

ConclusionEven in an area with previously high ascertainment, there has been a 45.9% increase in manifest Huntington disease over the last 30  years. Within our catchment area, prevalence varies between health board regions with similar community-based services. Such variation in prevalence could have major drug cost and service delivery implications, especially if expensive, complexly administered therapies prove successful. Health serv ices should gather accurate population-based data on a regional basis to inform service planning.
Source: Journal of Neurology - Category: Neurology Source Type: research