Cryo-EM structure of Mycobacterium smegmatis DyP-loaded encapsulin [Biochemistry]

Encapsulins containing dye-decolorizing peroxidase (DyP)-type peroxidases are ubiquitous among prokaryotes, protecting cells against oxidative stress. However, little is known about how they interact and function. Here, we have isolated a native cargo-packaging encapsulin from Mycobacterium smegmatis and determined its complete high-resolution structure by cryogenic electron microscopy (cryo-EM). This encapsulin comprises...

Source: Proceedings of the National Academy of Sciences - April 14, 2021 Category: Science Authors: Yanting Tang, An Mu, Yuying Zhang, Shan Zhou, Weiwei Wang, Yuezheng Lai, Xiaoting Zhou, Fengjiang Liu, Xiuna Yang, Hongri Gong, Quan Wang, Zihe Rao Tags: Biochemistry Biological Sciences Source Type: research