lncRNA transcription factor 7 is related to deteriorating clinical features and poor prognosis in multiple myeloma, and its knockdown suppresses disease progression by regulating the miR-203-mediated Jagged1-Notch1 signaling pathway

In conclusion, increased lnc-TCF7 expression was related to deteriorating clinical features and prognosis, and lnc-TCF7-knockdown inhibited disease progression by regulating the miR-203-mediated Jagged1-Notch1 signaling pathway activation in MM.PMID:33841573 | PMC:PMC8020383 | DOI:10.3892/ol.2021.12673

Source: Oncology Letters - April 12, 2021 Category: Cancer & Oncology Authors: Haiyan Liu Yaodong Shen Ya Xu Li Wang Chenlu Zhang Yijing Jiang Lemin Hong Hongming Huang Hong Liu Source Type: research