Targeted deep sequencing of bladder tumors reveals novel associations between cancer gene mutations and mutational signatures with major risk factors

CONCLUSIONS: These data quantify the contribution of BC risk factors to mutational burden and suggest different signature enrichments among never, former, and current smokers.PMID:33849962 | DOI:10.1158/1078-0432.CCR-20-4419

Source: Clinical Cancer Research - April 14, 2021 Category: Cancer & Oncology Authors: Stella Koutros Nina Rao Lee Moore Michael L Nickerson Donghyuk Lee Bin Zhu Larissa Pardo Dalsu Baris Molly Schwenn Alison Johnson Kristine Jones Montserrat Garcia-Closas Ludmila Prokunina-Olsson Debra T Silverman Nathaniel Rothman Michael Dean Source Type: research