Resistance to nitrofurantoin is an indicator of extensive drug-resistant (XDR) < em > Enterobacteriaceae < /em >

Conclusion. Nitrofurantoin resistance could be an indicator of the XDR phenotype among Enterobacteriaceae, harbouring multiple AMR and efflux pump genes. Tigecycline and colistin are the only antibiotics that could be used in the treatment of such XDR infections. A deeper understanding of the co-resistance mechanisms in XDR pathogens and prescription of AST-based appropriate combination therapy may help mitigate this problem.PMID:33830906 | DOI:10.1099/jmm.0.001347
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research