Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities
This study encourages further development of more potent inhibitors based on this chemical scaffold and provides a chemical tool to identify its cellular binding target.PMID:33845232 | DOI:10.1016/j.ejmech.2021.113417
Source: European Journal of Medicinal Chemistry - Category: Chemistry Authors: Cheng Zhang Hu Yue Ping Sun Lei Hua Shuli Liang Yitao Ou Dan Wu Xinyi Wu Hao Chen Ying Hao Wenhui Hu Zhongjin Yang Source Type: research