Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities

This study encourages further development of more potent inhibitors based on this chemical scaffold and provides a chemical tool to identify its cellular binding target.PMID:33845232 | DOI:10.1016/j.ejmech.2021.113417
Source: European Journal of Medicinal Chemistry - Category: Chemistry Authors: Source Type: research
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