MRI-derived PRECISE scores for predicting pathologically-confirmed radiological progression in prostate cancer patients on active surveillance

ConclusionThe PRECISE scoring system showed good overall performance, and the high NPV may help limit the number of follow-up biopsies required in patients on AS.Key Points• PRECISE scores 1–3 have high NPV which could reduce the need for re-biopsy during active surveillance.• PRECISE scores 4–5 have moderate PPV and should trigger either close monitoring or re-biopsy.• Three baseline predictors (PSA density, lesion size and Likert score) have a significant impact on the progression-free survival (PFS) time.
Source: European Radiology - Category: Radiology Source Type: research