High-impact exercise stimulated localised adaptation of microarchitecture across distal tibia in postmenopausal women

ConclusionWe demonstrated that it was possible to detect exercise-related bone adaptation with 3D registration of HR-pQCT scan data. Regular hopping exercise increased Tb.N and possibly BV/TV across the whole distal tibia. A novel finding of the study was that tBFR and tBRR responses to loading were localised: changes were achieved by formation rate exceeding resorption rate in the exercise leg, both globally and at the anterior region where turnover was greatest.Trial registrationclinicaltrials.gov: NCT03225703
Source: Osteoporosis International - Category: Orthopaedics Source Type: research