Genetic influences on externalizing psychopathology overlap with cognitive functioning and show developmental variation

CONCLUSIONS: Cognitive impairment may be a useful endophenotype of externalizing psychopathology and, therefore, help elucidate its pathophysiological underpinnings. Decreasing genetic variance suggests that gene discovery efforts may be more fruitful in children than adolescents or young adults.PMID:33785081 | DOI:10.1192/j.eurpsy.2021.21

Source: Journal of the Association of European Psychiatrists - March 31, 2021 Category: Psychiatry Authors: Josephine Mollon Emma E M Knowles Samuel R Mathias Amanda Rodrigue Tyler M Moore Monica E Calkins Ruben C Gur Juan Manuel Peralta Daniel J Weiner Elise B Robinson Raquel E Gur John Blangero Laura Almasy David C Glahn Source Type: research