Effects of dehydroepiandrosterone (DHEA) on follicular dynamics in a diminished ovarian reserve in vivo model.

In conclusion, our findings suggest that DHEA administration in DOR rats due to VCD results in a larger follicular pool. Decreased atresia may be one of the possible effects of DHEA in DOR cases. Whatever the mechanism, DHEA treatment potentially may be useful clinically as a means to increase the number of gonadotropin-responsive follicles for ovarian stimulation.
PMID: 25671506 [PubMed - as supplied by publisher]

Source: Systems Biology in Reproductive Medicine - February 11, 2015 Category: Reproduction Medicine Authors: Hassa H, Aydin Y, Ozatik O, Erol K Tags: Syst Biol Reprod Med Source Type: research