Genetic effect of < em > MTHFR < /em > C677T, A1298C, and A1793G polymorphisms on the age at onset, plasma homocysteine, and white matter lesions in Alzheimer's disease in the Chinese population

CONCLUSIONS: The genotype distributions of C677T and A1298C polymorphisms are associated with AD in the Chinese population. Moreover, AD patients with C677T polymorphism are prone to present an earlier onset, higher homocysteine level, and more severe WML.PMID:33833133 | DOI:10.18632/aging.202827

Source: Aging - April 9, 2021 Category: Biomedical Science Authors: Yaling Jiang Xuewen Xiao Yafei Wen Meidan Wan Lu Zhou Xixi Liu Xin Wang Lina Guo Hui Liu Yafang Zhou Junling Wang Xinxin Liao Lu Shen Bin Jiao Source Type: research